BRCA genes: human genes that produce tumor suppressor proteins that help repair damaged DNA. BRCA1, located on chromosome 17 and BRCA2, located on chromosome 13 have been known to cause inherited breast cancer. People with BRCA1 and BRCA2 mutations have children with 50% chance of possessing the same autosomal dominant mutation in those genes. If a person does not have a family history, the risk of developing breast cancer is up to 33% in 70 years of age, but a person with a family history most likely have the risk up to 58% in 50 years of age.